Tools and techniques for solvent selection: green solvent selection guides

Aided Solvent Selection and Design Framework

Greener Solvent Selection, Solvent Recycling and Optimal Control for Pharmaceutical and Bio-processing Industries

This paper proposes the simultaneous integration of environmentally benign solvent selection (chemical synthesis), solvent recycling (process synthesis) and optimal control for the separation of azeotropic systems using batch distillation. The previous work performed by Kim et al. (2004) combines the chemical synthesis and process synthesis under uncertainty. For batch distillation, optimal ope...

Extraction solvent selection in environmental analysis.

A method for the prediction of a suitable solvent for the extraction of pesticides is outlined. The procedure is based on the Hildebrand solubility parameter, delta(t). The solubility parameter is broken down into three individual components, which are calculated by the addition of group contributions. To demonstrate the applicability of the approach pressurized fluid extraction was used to ext...

Solvent replacement for green processing.

The implementation of the Montreal Protocol, the Clean Air Act, and the Pollution Prevention Act of 1990 has resulted in increased awareness of organic solvent use in chemical processing. The advances made in the search to find "green" replacements for traditional solvents are reviewed, with reference to solvent alternatives for cleaning, coatings, and chemical reaction and separation processes...

Solvent selection evaluation tools for an early stage at pharmaceutical process

A first level of a methodology for the selection and evaluation of solvent at an early stage is presented inside a programming tool for its systematic and friendly application. This first level is based on properties and characteristics of solvents for their selection. Different tools are integrated into the program to aid the evaluation of the group of solvents selected. A case study is presen...